INDOLINE-6-CARBOXYLIC ACID - Names and Identifiers
INDOLINE-6-CARBOXYLIC ACID - Physico-chemical Properties
| Molecular Formula | C9H9NO2
|
| Molar Mass | 163.17326 |
INDOLINE-6-CARBOXYLIC ACID - Introduction
INDOLINE-6-CARBOXYLIC ACID(INDOLINE-6-CARBOXYLIC ACID) is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: INDOLINE-6-CARBOXYLIC ACID is white to off-white crystalline powder.
-Solubility: It is slightly soluble in water and ethanol, and more soluble in chloroform and dichloromethane.
-Melting point: Its melting point depends on the crystalline form and is generally 110-115 ° C.
-Chemical properties: INDOLINE-6-CARBOXYLIC ACID is an acidic compound that can react with bases to form salts. It can also be further oxidized to indolinecarboxaldehyde or indolecarboxylic acid.
Use:
-Chemical synthesis: INDOLINE-6-CARBOXYLIC ACID is an important intermediate and is widely used in drug synthesis and natural product synthesis.
-Biological research: It is also used as a biological marker and bioanalytical reagent to study cell signaling, enzyme activity and metabolic pathways.
Method:
-The preparation of INDOLINE-6-CARBOXYLIC ACID is generally carried out through the following steps:
1. First, the indole compound reacts with sodium cyanide under alkaline conditions to produce sodium salt of indole.
2. Then, the indole sodium salt reacts with carbon dioxide to form a stable ketone complex.
3. Finally, the ketone complex is hydrolyzed by ACID to obtain INDOLINE-6-CARBOXYLIC ACID.
Safety Information:
- INDOLINE-6-CARBOXYLIC ACID is a relatively safe compound under normal operation.
-However, as a chemical substance, it may be irritating to the human body, so safe operation guidelines should be followed during operation.
-Avoid inhaling dust or contact with skin and eyes.
-If exposed to the compound, immediately flush the affected area with clean water and seek medical advice.
Last Update：2024-04-09 21:01:54